Product Description: Alprenolol ((RS)-Alprenolol; dl-Alprenolol) hydrochloride is an orally active non-selective β-adrenoceptor antagonist and an antagonist of 5-HT1A and 5-HT1B receptors. Alprenolol hydrochloride is used as an anti-hypertensive, anti-anginal and anti-arrhythmic agent[1][2][3].
Applications: Cancer-programmed cell death
Formula: C15H24ClNO2
Citations: Cell Rep Methods. 2023 Oct 23;3(10):100599./Nat Chem Biol. 2023 Aug 14./bioRxiv. 2020 Jan./J Chromatogr B. 2023 Jun 20, 123804./J Pharmaceut Biomed. 2020, 113870./Nat Commun. 2020 Sep 25;11(1):4857./Sci Total Environ. 2024 May 13:933:173244.
References: [1]Himori N, et al. Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs. Arch Int Pharmacodyn Ther. 1977 Jan;225(1):152-65./[2]Fernández-Guasti A, et al. Evidence for the involvement of the 5-HT1A receptor in the anxiolytic action of indorenate and ipsapirone. Psychopharmacology (Berl). 1990;101(3):354-8./[3]Parratt JR, et al. Myocardial and haemodynamic effects of the beta-adrenoceptor blocking drug alprenolol (H56/28) in anaesthetized cats. Br J Pharmacol. 1969 Oct;37(2):357-66.
CAS Number: 13707-88-5
Molecular Weight: 285.81
Compound Purity: 99.76
Research Area: Cancer; Cardiovascular Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 50 mg/mL (ultrasonic)
Target: 5-HT Receptor
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