AM966, CAS 1228690-19-4

Product Description: AM966 is a high affinity, selective, oral LPA1-antagonist, inhibits LPA-stimulated intracellular calcium release (IC50=17 nM).

Applications: COVID-19-immunoregulation

Formula: C27H23ClN2O5

References: [1]Swaney, JS, et al. A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model. Br J Pharmacol. 2010 Aug;160(7):1699-713./[2]Olianas MC, et al. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochem Pharmacol. 2015 Jun 15;95(4):311-23.

CAS Number: 1228690-19-4

Molecular Weight: 490.93

Compound Purity: 99.86

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: LPL Receptor

• Artikelnummer: MEXHY-15277-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15277-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK