AMG 511, CAS 1253573-53-3

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 4-[2-[(5-fluoro-6-methoxy-3-pyridinyl)amino]-5-[(1R)-1-[4-(methylsulfonyl)-1-piperazinyl]ethyl]-3-pyridinyl]-6-methyl-1,3,5-triazin-2-amine

Purity: ≥98%

Formula Markup: C22H28FN9O3S

Formula Weight: 517.580983

CAS Number: 1253573-53-3

Notes: An inhibitor of class I PI3Ks; selective for PI3K over 372 other protein kinases at 1 µM; inhibits Akt phosphorylation in U87MG cells (IC50 = 4 nM); reduces tumor growth in a U87MG mouse xenograft model at doses of 1, 3, and 10 mg/kg per day

• Artikelnummer: CAY41853-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41853-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK