(Aminooxy)acetamide-Val-Cit-PAB-MMAE, CAS 2446645-88-9

Product Description: (Aminooxy)acetamide-Val-Cit-PAB-MMAE (MMAE 5) is an intermediate used in the synthetic preparation of drug-linker conjugates for ADC. (Aminooxy)acetamide-Val-Cit-PAB-MMAE is conjugated to polyamide via oxime bond formation to form MMAE polyamide conjugate. Then MMAE polyamide conjugate can be conjugated to Trastuzumab, to make ADC[1].

Applications: Cancer-programmed cell death

Formula: C60H97N11O14

References: [1]Ouberai Myriam, et al. Preparation of antibody-drug conjugates using polymers and crosslinkers. World Intellectual Property Organization, WO2020128488 A1. 2020-06-25.

CAS Number: 2446645-88-9

Molecular Weight: 1196.48

Compound Purity: 97.01

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Drug-Linker Conjugates for ADC

• Artikelnummer: MEXHY-153263-5
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-153263-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK