Product Description: AMZ30 is a highly effective inhibitor of phosphatase PME-1 with an IC50 value of 600nM. It selectively reduces demethylated PP2A in cells.
Formula: C19H12FN3O6S2
References: [1]Bachovchin DA, et al. Discovery and optimization of sulfonyl acrylonitriles as selective, covalent inhibitors of protein phosphatase methylesterase-1. J Med Chem. 2011 Jul 28;54(14):5229-36.