Anacetrapib, CAS 875446-37-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[4'-fluoro-2'-methoxy-5'-(1-methylethyl)-4-(trifluoromethyl)[1,1'-biphenyl]-2-yl]methyl]-4-methyl-2-oxazolidinone

Purity: ≥98%

Formula Markup: C30H25F10NO3

Formula Weight: 637.5

CAS Number: 875446-37-0

Notes: Anacetrapib is an inhibitor of cholesterol ester transfer protein (CETP) with IC50 values of 17 and 15 nM for CETP-dependent transfer of cholesterol esters and triglycerides, respectively.{18510} It decreases plasma levels of LDL and triglycerides, reduces atherosclerotic lesion sizes, and increases HDL levels in the E3L.CETP mouse model of atherosclerosis.{42509} Anacetrapib (150 mg/kg) increases HDL levels by 2-fold and lowers LDL and fasting plasma triglyceride levels in rhesus macaques.{42510}

• Artikelnummer: CAY21558-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21558-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK