Anti-11-Deoxycortisol (CET-M8)

Anti-11-Deoxycortisol [CET-M8], Recombinant, F(ab)2 kappa, Human

CloneID: CET-M8

Heavy Chain modification: AbFab2™ His-Tagged

Antigen Long Description: 4-(2-carboxyethylthio)-11-deoxycortisol linked to bovine serum albumin.

Origin Pub PMID: 1922102

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: Binds specifically to 11-deoxycortisol. No cross-reactivity with cortisol or cortisone.

Application Notes (Clone): The antibody binds specifically to 11-Deoxycortisol, a glucocorticoid steroid hormone which can be oxygenated to cortisol. The monoclonal antibody recognises the functional groups at C-11 and C-21 in the steroid portion of 11-deoxycortisol, and can be useful in determining plasma levels of deoxycortisol in the metyrapone test in the diagnosis of Cushing's syndrome and adrenal insufficiency.

• Artikelnummer: ABAAb00402-10.7
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00402-10.7
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Klonalität: Recombinant
• Methode: ELISA, Radioimmunoassay (RIA)
• Isotyp: F(ab)2 kappa
• Wirt: Human