CloneID: 3B10B7
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with β-bungarotoxin (β-BGT).
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q9PTA2
Specificity Statement: This antibody binds β-bungarotoxin (β-BGT). Beta-1-bungarotoxin is a presynaptic neurotoxin of the venom. The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels (Kv).
Application Notes (Clone): The initial binding characterization of this antibody towards beta-bingarotoxin was done using ELISA. This antibody in combination with antibody 2B10E7 was used fro the development of a colloidal gold immunological lateral flow detection kit (CN114560934).
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