Anti-Blood group A antigen (AC1001)

Anti-Blood group A antigen [AC1001], Recombinant, scFv fragment (His)

CloneID: AC1001

Heavy Chain modification: ScFv

Antigen Long Description: The original antibody was produced by immunizing mice with A₁ erythrocytes and with blood group A substance.

Origin Pub PMID: 3115981

Buffer Composition: PBS only.

Chimeric Use Statement: This reformatted scFv antibody, based on the original IgM format, created for improved compatibility with existing reagents, assays and techniques.

Specificity Statement: This antibody is specific for blood group antigen A.

Application Notes (Clone): This antibody was used in a quantitative precipitin assay, a hemagglutination assay (HA), inhibition assays (by ELISA). In the HA with human erythrocytes, the antibody reacted with the A₁ and A₂ subtypes (showing double the sensitivity towards the A₁ subtype) (Chen and Kabat, 1985; PMID: 2414276). The structure of the scFv version of this antibody was determined via crystallization (Thomas et al., 2002; PMID: 11679577).

• Artikelnummer: ABAAb04235-30.11-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04235-30.11-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: scFv fragment (His)