Anti-BMP receptor type IA (AbD1556)

Anti-BMP receptor type IA [AbD1556], Recombinant, IgG1 lambda, Mouse

CloneID: AbD1556

Antigen Long Description: Biotinylated BMPR-IA immobilized on a resin.

Buffer Composition: PBS only.

Chimeric Use Statement: This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P36894

Specificity Statement: The antibody binds to human BMPR-IA with a low nanomolar affinity.

Application Notes (Clone): This antibody binds to human BMPR-1A, which, on ligand bindingg, forms a receptor complex acting as a serine/threonine kinase, activating SMAD transcriptional regulators. They positively regulate chondrocyte differentiation, for example. The antibody neutralizes BMP-binding to the receptor.

• Artikelnummer: ABAAb00426-1.1-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00426-1.1-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA, Blocking, Super-Resolution Microscopy
• Isotyp: IgG1 lambda
• Wirt: Mouse