Anti-C3 (C3-2)

Anti-C3 [C3-2], Recombinant, IgG1 kappa, Human

CloneID: C3-2

Antigen Long Description: The original antibody was generated by immunizing mice with purified human C3.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P01024

Specificity Statement: The antibody interacts specifically with native C3, containing an intact thioester bond and not with an inactive form of C3, containing a hydrolysed ester bond. The epitope in part located on the 23kD-α-chain fragment of C3c.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The binding affinity of the humanised version of the antibody to native C3 was measured by surface plasmon resonance (Kd= 5.9 nM). The murine and the humanised version of the antibody could inhibit the activation of C3 (WO2004031240A1).

• Artikelnummer: ABAAb03806-10.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03806-10.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Western Blotting, ELISA, Super-Resolution Microscopy, Inhibition
• Isotyp: IgG1 kappa
• Wirt: Human