CloneID: 3G7
Heavy Chain modification: AbFab2™ His-Tagged
Antigen Long Description: The 2e loop of the C3a receptor.
Origin Pub PMID: 11373092
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original mouse scFv format for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q16581
Specificity Statement: Binds specifically to the 2e loop of the human C3a receptor, residues 185-193.
Application Notes (Clone): This scFv antibody binds to the 2e loop of the human C3a receptor, a G protein-coupled receptor stimulating chemotaxis, superoxide anion generation and granule enzyme release.
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