CloneID: 1G5
Antigen Long Description: The original antibody was generated by immunizing mice with canine distemper virus CVCC AV299 strain.
Buffer Composition: PBS only.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds canine distemper virus (CDV). Canine distemper is a viral disease caused by CDV that attacks the respiratory, gastrointestinal and nervous systems of puppies and dogs. The virus can also be found in wildlife such as foxes, wolves, coyotes, raccoons, skunks, mink and ferrets and has been reported in lions, tigers, leopards and other wild cats as well as seals.
Application Notes (Clone): This antibody shows neutralizing activity towards canine distemper virus. This antibody was used as detection antibody in combination with another anti-canine distemper virus antibody 6E11 as a capture antibody in a sandwich ELISA. In vivo studies to detect the efficiency of this antibody in preventing infections and protecting against canine distemper virus indicated that this antibody can alleviate the clinical symptoms caused by canine distemper virus, reduce the mortality rate and reduce the number of days of detoxification, and have a good therapeutic and/or preventive effect (CN105695420).
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