CloneID: cAb4729
Antigen Long Description: The antibody 3G5 was generated by immunizing BALB/c mice with recombinant CCHFV protein. The CDRs of the parental mouse antibody 3G5 were grafted onto human framework regions to generate this humanized antibody.
Origin Pub PMID: 36496007
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P89522
Specificity Statement: This antibody binds CCHFV. Crimean-Congo Haemorrhagic Fever virus (CCHFV) is a tick-borne pathogen belonging to the genus Orthonairovirus of the family Nairoviridae within the order Bunyavirales that is responsible for the disease Crimean-Congo haemorrhagic fever (CCHF). CCHF is a zoonotic disease typically spread by tick bites or close contact with the blood, secretions, organs or other bodily fluids of infected persons or animals. The CCHF virus causes severe viral haemorrhagic fever outbreaks, with a case fatality rate of 10–40%.
Application Notes (Clone): The antibody was capable of detecting the recombinant CCHFV nuceloprotein in an ELISA (PMID: 36496007).
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