Anti-CD11a (hu1124 (Efalizumab))

Anti-CD11a [hu1124 (Efalizumab)], Recombinant, IgG1 kappa, Human

CloneID: hu1124 (Efalizumab)

Heavy Chain modification: Fc Silent™

Antigen Long Description: Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.

Buffer Composition: PBS only.

Chimeric Use Statement: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Uniprot Accession No.: P20701

Specificity Statement: Binds to human LFA-1.

Application Notes (Clone): Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.

• Artikelnummer: ABAAb00535-10.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00535-10.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Flow Cytometry, Blocking
• Isotyp: IgG1 kappa
• Wirt: Human