CloneID: OX-130
Antigen Long Description: Recombinant SIRPβ1 was purified by nickel affinity chromatography and used to immunize mice.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: O00241
Specificity Statement: This antibody recognizes both common alleles of the human activating SIRPβ1 receptor, does not recognize SIRPγ, but cross-reacts with one of the common alleles of the inhibitory human SIRPα receptor.
Application Notes (Clone): This antibody binds both common alleles of the human activating SIRPβ1 receptor, but ELISA and surface plasmon resonance results have shown that it reacts with one of the two common alleles of SIRPα, potentially yielding different outcomes when this antibody is used in assays from different individuals.
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