Anti-CD19 (1D3)

Anti-CD19 [1D3], Recombinant, IgG kappa, Rabbit

CloneID: 1D3

Buffer Composition: PBS only.

Uniprot Accession No.: P25918

Specificity Statement: The antibody is specific for mouse CD19.

Application Notes (Clone): The scFv fragment of the antibody was employed in the generation of a chimeric antigen receptor (CAR) which bound to CD19. Mice were administered mouse CAR-expressing cells or control cells. Anti-muCD19 CAR-T mice exhibited elevated serum IL-6 levels on day 2 after CAR-T administration, with a decrease at day 5, compared to control mice that exhibited very low or no increase in serum IL-6 levels. A20 tumor bearing mice were administered CPA and anti -mouse CD 19 CAR-T cells and evaluated for various parameters. Animals treated with CPA and anti-mouse CD 19 CAR-T cells were observed to have elevated levels of serum cytokines, as compared to controls (EP3644721A1).

• Artikelnummer: ABAAb03688-23.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03688-23.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Klonalität: Recombinant
• Methode: Flow Cytometry
• Isotyp: IgG kappa
• Wirt: Rabbit