Anti-CD2 (OX-34)

Anti-CD2 [OX-34], Recombinant, IgG2a kappa, Mouse

CloneID: OX-34

Antigen Long Description: OX-34 was prepared by immunizing mice with T blasts prepared inmixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.

Buffer Composition: PBS only.

Uniprot Accession No.: P08921

Specificity Statement: OX-34 binds specifically to rat CD2. CD2 is type I membrane protein involved in triggering of T-cells (cytoplasmic domain is involved in signaling function) and is expressed on thymocytes, peripheral T cells, dendritic epidermal T cells, macrophages in the spleen, and NK cells.

Application Notes (Clone): Ox34 blocks CD48 binding to CD2 causing partial block of T cell activation; OX34 can be used to deplete peripheral T cells (used to prevent allograft rejection in vivo).

• Artikelnummer: ABAAb00559-2.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00559-2.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Rat (Rattus)
• Klonalität: Recombinant
• Methode: Flow Cytometry, Blocking
• Isotyp: IgG2a kappa
• Wirt: Mouse