CloneID: 9D11B6E6
Antigen Long Description: The original antibody was generated by immunizing mice with CD23.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P06734
Specificity Statement: The antibody is specific for CD23. CD23 is a low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. It has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).
Application Notes (Clone): The antibody 9D11B6E6 and the commercial antibody SP23 were used to stain B-cell lymphoma. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 9D11B6E6 was higher than the commercial antibody. The antibody and the commercially available antibody SP23 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN112442124B).
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