CloneID: 185.IG2
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by immunizing a mouse with CD36.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG2a format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P16671
Specificity Statement: This antibody is specific for the CD36 protein.
Application Notes (Clone): The original version of this antibody was used for immunoprecipitation on human blood platelets It was able to aggregate the same proteins as other CD36 specific antibodies (Miao et al., 2001; PMID:11238109). Further this antibody was used for immunohistochemistry on normal placentas and placentas infected with malaria (Hromatka et al., 2013; PMID:23575149), and on healthy and cancerous lymph nodes (Martens et al., 2006; PMID:16440291). This antibody was also used for immunofluorescence on healthy and cancerous lymph nodes to study lymph node sinuses as the primary site of tumour cell arrest upon regional lymph node metastasis (Martens et al., 2006; PMID:16440291). Finally this antibody was used to block the CD36 protein (Davies et al., 2001; PMID:11279149) (McIntyre et al., 2002; PMID:12502787) (Lopez-Vilchez et al., 2011; PMID:21641410).
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