CloneID: OX-49
Heavy Chain modification: Fc Silent™
Antigen Long Description: T blasts from a mixed lymphocyte reaction between purified rat CD4+ T cells and irradiated spleen.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody binds rat CD44 at an epitope overlapping with asparagine residue 67. The murine homologue of CD44 has a histidine in this position which is sufficient to abrogate binding (Zheng et al. 1995).
Application Notes (Clone): This antibody antibody recoginses rat CD44.