Anti-CD47 (C47B227)

Anti-CD47 [C47B227], Recombinant, IgG2b kappa, Mouse

CloneID: C47B227

Antigen Long Description: Three de novo phage libraries displaying Fab variants on phage coat protein pIX were panned against biotinylated human CD47.

Buffer Composition: PBS only.

Uniprot Accession No.: Q08722

Specificity Statement: The antibody is specific for CD47. The antibody binds a conformational epitope composed of residues in the C’C’’ loop (L54) and B-strand C*’ (K56 and T58) regions.

Application Notes (Clone): The structure of the Fab fragment in complex with CD47 was determined. The binding affinity of the antibody to human and cyno CD47 were measured (Kd= 1nM and 0,5 nM respectively). The antibody inhibited CD47 from interacting with SIRP alpha (US10864268).

• Artikelnummer: ABAAb03167-3.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03167-3.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Inhibition
• Isotyp: IgG2b kappa
• Wirt: Mouse