CloneID: NbCEA5
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P06731
Specificity Statement: This antibody is specific for human CEACAM5
Application Notes (Clone): The binding of the original version of this antibody (VHH) to CEACAM5 was characterized in an SPR (KD 0.41 nM), ELISA (EC50 of 0.026 nM), and FACS (EC50 of 1.0 nM). In its bi-specific construction with Ab04389 (Anti-EGFR [7D12]), it served as an anchor (US20220242958).