Anti-CNPS (3E5)

Anti-CNPS [3E5], Recombinant, IgG3 kappa, Mouse
Artikelnummer
ABAAb00354-5.0
Verpackungseinheit
200 μg
Hersteller
Absolute Antibody

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CloneID: 3E5

Antigen Long Description: A covalent serotype A Glucuronoxylomannan (GXM) -tetanus toxoid conjugate (GXM-TT).

Origin Pub PMID: 23911417

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Specificity Statement: Specifically binds to CNPS.

Application Notes (Clone): This antibody binds to Glucuronoxylomannan (GXM), which is the main constituent of the C. neoformans capsule and modulates the inflammatory response of monocytes. In a later study conducted by Yuan et al. 1998 (PMID: 9488395), it was shown that switching the original murine IgG3 antibody to other IgG subtypes, in particular IgG2A, significantly prolonged animal survival in an infection model.
Mehr Informationen
Artikelnummer ABAAb00354-5.0
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab00354-5.0
Verpackungseinheit 200 μg
Mengeneinheit STK
Reaktivität Various species
Klonalität Recombinant
Methode ELISA
Isotyp IgG3 kappa
Wirt Mouse
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