Anti-CNPS (3E5)

Anti-CNPS [3E5], Recombinant, IgG3 kappa, Mouse

CloneID: 3E5

Antigen Long Description: A covalent serotype A Glucuronoxylomannan (GXM) -tetanus toxoid conjugate (GXM-TT).

Origin Pub PMID: 23911417

Buffer Composition: PBS only.

Specificity Statement: Specifically binds to CNPS.

Application Notes (Clone): This antibody binds to Glucuronoxylomannan (GXM), which is the main constituent of the C. neoformans capsule and modulates the inflammatory response of monocytes. In a later study conducted by Yuan et al. 1998 (PMID: 9488395), it was shown that switching the original murine IgG3 antibody to other IgG subtypes, in particular IgG2A, significantly prolonged animal survival in an infection model.

• Artikelnummer: ABAAb00354-5.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00354-5.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG3 kappa
• Wirt: Mouse