Anti-CTLA-4 (4.1.1)

Anti-CTLA-4 [4.1.1], Recombinant, IgG2 kappa, Human

CloneID: 4.1.1

Heavy Chain modification: Fc Silent™

Antigen Long Description: The original antibody was generated immunizing transgenic mice with CTLA-4.

Buffer Composition: PBS only.

Chimeric Use Statement: This is a reformatted human IgG2 Fc Silent™ antibody, based on the original human IgG2 format, created for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P16410

Specificity Statement: The antibody is specific for CTLA-4. The antibody bind to human, cynomologous, and marmoset CTLA4.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. T cell blast/Raji assay showed an enhancement of IL-2 production in human T cells induced by the antibody. The antibody showed an affinity of 1.63*10^-10 1/M (MN100001982A1).

• Artikelnummer: ABAAb03930-11.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03930-11.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human, Primate, Cynomolgus Monkey (Primate)
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG2 kappa
• Wirt: Human