Anti-CXCR4 (14D09)

Anti-CXCR4 [14D09], Recombinant, VHH, Camelid

CloneID: 14D09

Heavy Chain modification: His-tagged

Buffer Composition: PBS only.

Uniprot Accession No.: P61073

Specificity Statement: This antibody is specific for CXCR4.

Application Notes (Clone): The binding of the original version of this antibody (VHH) to CXCR4-expressing viral lipoparticles was characterized in an ELISA. Furthermore, it was analyzed for its ability to compete with the ligand CXCL12 (or SDF-1a) for receptor binding by displacement of biotinylated SDF-1 on Caki-CXCR4 cells in flow cytometry. This antibody exhibited medium affinity to its target (EC₅₀/kD of 1 < x ≤ 10 nM) and a ligand inhibition (IC₅₀ 1 < x < 10 nM). In its bi-specific construction with clone 57A07, it served a functional role (US20220242958).

• Artikelnummer: ABAAb04368-34.11-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04368-34.11-BT
• Verpackungseinheit: 500 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA, Flow Cytometry
• Isotyp: VHH
• Wirt: Camelid