CloneID: DA24cB7
Heavy Chain modification: ScFv
Antigen Long Description: The original antibody was originated from a scFv phage library obtained from a sheep hyperimmunised with DA-BSA conjugate. It was isolated by panning against DA.
Origin Pub PMID: 27879646
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted sheep scFv antibody, based on the original sheep scFv format, created for improved compatibility with existing reagents, assays and techniques.
Specificity Statement: The antibody is specific for domoic acid. Domoic acid is a kainic acid-type neurotoxin that causes amnesic shellfish poisoning. It is produced by algae and accumulates in shellfish, sardines, and anchovies. When sea lions, otters, cetaceans, humans, and other predators eat contaminated animals, poisoning may result.
Application Notes (Clone): The specificity of the original format of the antibody was confirmed by competitive ELISA using plates coated with DA-OVA (I50 of 1.21 ng/mL (3.9 nM)). The assay was used for the determination of DA levels in shellfish extracts (Shaw et al., 2008; PMID: 18384202).
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