Anti-Envelope glycoprotein H; Envelope glycoprotein L (Fab-RC)

Anti-Envelope glycoprotein H; Envelope glycoprotein L [Fab-RC], Recombinant, IgG1 kappa, Human

CloneID: Fab-RC

Antigen Long Description: The original antibody was raised from the white blood cells of a human individual immunized with zoster vaccine.

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q775J3; Q9J3N1

Specificity Statement: This antibody is specific for the combination of gH and gL and does not detect the proteins in isolation.

Application Notes (Clone): The original antibody was used for surface plasmon resonance on VZV gHgL. This antibody was used for a neutralization assay. Here is showed it was able to inhibit gB/gHgL-mediated membrane fusion. The structure of this antibody was determined using x-ray crystallography (Xing et al., 2015; PMID:25918416). This antibody was used for immunohistochemistry on fixed and unfixed VZV-infected and control HFL cells. This antibody was also used for a plaque reduction assay on VZV-infected HFL cells. Further this antibody was used for immunoprecipitation on VZV-infected and uninfected HFL cells (Birlea et al., 2013; PMID:23077312).

• Artikelnummer: ABAAb04452-10.0
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04452-10.0
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Virus
• Klonalität: Recombinant
• Methode: Immunoprecipitation, Immunohistochemistry, Neutralization, Super-Resolution Microscopy, Crystallography
• Isotyp: IgG1 kappa
• Wirt: Human