CloneID: H107
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with human heart ferritin.
Origin Pub PMID: 7476997
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P02794
Specificity Statement: This antibody binds the H subunit of human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
Application Notes (Clone): The binding characterization of this antibody for H subunit of ferritin was done using ELISA and immunoprecipitation (PMID: 3089283).