CloneID: DV9
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with bovine serum albumin conjugated fumonisin B1 (FMB1-BSA).
Buffer Composition: PBS only.
Chimeric Use Statement: This full-length reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody is specific for fumonisin B1. It does not react with other toxins like ochratoxin A, aflatoxin B1 and deoxynivalenol. Fumonisin B1 (FB1) is a mycotoxin produced by the various species of Fusarium fungus specifically, Fusarium verticillioides which commonly infects corn, wheat and other agricultural products. FB1 is neurotoxic, hepatotoxic, and nephrotoxic in animals, and it has been classified as a possible carcinogen to humans.
Application Notes (Clone): This antibody can be used to detect fumonisin B1 in a contaminated sample. This antibody reacts with fumonisin B1 in an ELISA assay. It was reported that the scFv version of this antibody showed 12 fold lower binding activity towards FMB(1)-BSA as compared to the parental whole IgG antibody (PMID: 19597742).
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