CloneID: Fab-1791
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: O75084
Specificity Statement: The antibody is specific for FZD7. The antibody recognises human FZD7, but not with mouse FZD7.
Application Notes (Clone): The antibody detected the recombinant human FZD7 by western blot analysis. The antibody reduced FZD7 signaling in breast cancer cell line MDA- B-231 about 3-fold. This antibody was used for detection of FZD7 expressed on OVCAR4 cells by flow cytometry. The antibody could block migration of a breast cancer cell line and ovarian cancer cell line OVCAR4. This antibody was used for immunohistochemistry on ovarian carcinoma and renal cell carcinoma samples (WO2016205566A1).