CloneID: C3
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was raised by immunizing a mouse with heat-inactivated poliovirus.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG2a format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P03300
Specificity Statement: This antibody is specific for the VP1 protein of poliovirus type 1.
Application Notes (Clone): The original antibody was used for a neutralization assay on poliovirions. Further this antibody was used for an attachment assay on HeLa cells and poliovirions (Wien et al., 1995; PMID:75397110). This antibody showed specificity for the VP1 protein of the type 1 poliovirus in immunoprecipitation of VP1, VP2 and VP3 of the type 1 poliovirus (Blondel et al., 1983; PMID:6190311, Van der Werf et al., 1983; PMID:6308670).
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