Anti-Ghrelin (5A1)

Anti-Ghrelin [5A1], Recombinant, IgG1 kappa, Mouse
Artikelnummer
ABAAb03853-1.1
Verpackungseinheit
100 μg
Hersteller
Absolute Antibody

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CloneID: 5A1

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: Q9UBU3

Specificity Statement: The antibody recognises ghrelin. Ghrelin is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach and is often called a "hunger hormone" because it increases the drive to eat.

Application Notes (Clone): The kinetic constant of the humanized, affinity matured Fab version of the antibody was measured by KinExA (Kd= 1 pM). The binding affinity of the Fab fragment to Ghrelin was measured by surface plasmon resonance (Kd= 2 pM). Rats were injected with human ghrelin and their food consumption was measured. Results showed that if the humanized Fab version of the antibody was administrated, their food consumption was effectively reduced (US7479271).
Mehr Informationen
Artikelnummer ABAAb03853-1.1
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab03853-1.1
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Surface Plasmon Resonance (SPR), In Vivo Assay
Isotyp IgG1 kappa
Wirt Mouse
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