Anti-Ghrelin (5A1)

Anti-Ghrelin [5A1], Recombinant, IgG1 kappa, Mouse

CloneID: 5A1

Buffer Composition: PBS only.

Uniprot Accession No.: Q9UBU3

Specificity Statement: The antibody recognises ghrelin. Ghrelin is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach and is often called a "hunger hormone" because it increases the drive to eat.

Application Notes (Clone): The kinetic constant of the humanized, affinity matured Fab version of the antibody was measured by KinExA (Kd= 1 pM). The binding affinity of the Fab fragment to Ghrelin was measured by surface plasmon resonance (Kd= 2 pM). Rats were injected with human ghrelin and their food consumption was measured. Results showed that if the humanized Fab version of the antibody was administrated, their food consumption was effectively reduced (US7479271).

• Artikelnummer: ABAAb03853-1.1-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab03853-1.1-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Surface Plasmon Resonance (SPR), In Vivo Assay
• Isotyp: IgG1 kappa
• Wirt: Mouse