Anti-gp120 protein (CD4-binding domain) (559/64-D)

Anti-gp120 protein (CD4-binding domain) [559/64-D], Recombinant, IgG1 kappa, Human
Artikelnummer
ABAAb03845-10.0
Verpackungseinheit
100 μg
Hersteller
Absolute Antibody

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CloneID: 559/64-D

Antigen Long Description: The antibody was generated by fusing Ab-producing cells pooled from two separate patients.

Origin Pub PMID: 25965315

Buffer Composition: PBS with 0.02% Proclin 300.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P03377

Specificity Statement: The antibody recognises a conformational epitopes of the gp120 envelope protein of HIV-1.

Application Notes (Clone): The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody was able to block the interaction between recombinant CD4 (rCD4) and rgp120. It was also able to achieve 50% neutralization of HTLV-IIIB and MN strains of HIV-1 in a concentration range of 0.5-12.8 micrograms/mL. The binding affinity of the antibody for gp120 in solution was measured, dissociation constants (Kd) equal to 40 nM.
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Artikelnummer ABAAb03845-10.0
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab03845-10.0
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Various species
Klonalität Recombinant
Methode ELISA, Blocking, Neutralization
Isotyp IgG1 kappa
Wirt Human
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