CloneID: hCG-H14
Antigen Long Description: The original antibody was generated by immunizing a male Llama glama with RR6 azo dye coupled with bovine serum albumin.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P01233
Specificity Statement: This antibody is specific for the alpha subunit of the human chorionic gonadotropin hormone (hCG), a hormone produced by a part of the placenta, the syncytiotrophoblast, following implantation. The hormone has an important role during pregnancy, as it interacts with the LHCG receptor in the ovaries to prevent the degeneration of the corpus luteum, and thereby allows the secretion of progesterone during the first trimester. hCG is a heterodimeric glycoprotein, composed of an α and a β domain, of which the α is identical to that of LH and FSH, while the β is unique to hCG.
Application Notes (Clone): This antibody can be used for the detection of presence of hCG in a sample. The binding specificity of this antibody towards alpha subunit of hCG was determined using ELISA. This antibody was reported to bind hCG with a binding affinity of 300-400 nM (PMID: 10209277).
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