Anti-IL-17A Neutralizing Antibody

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Applications: Useful for binding studies and for the inhibition of IL-17RA:IL-17A interactions.

Assay Conditions: Antibody was added atvarious concentrations using the IL-17RA[Biotin]:IL-17A Inhibitor Screeningbinding assay (BPS Cat. #72060). Assay wasperformed according to the recommendedprotocol.

Description: Neutralizing recombinant humanchimeric antibody recognizing human IL-17A.This antibody has not been tested for crossreactivitywith other species.

Format: Aqueous buffer solution

Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

Purification: Purified using protein A affinitychromatography from HEK293 supernatants.

Storage Stability: Stable for at least 12 months at-80°C.

Uniprot: Q16552

Warnings: Avoid freeze/thaw cycles. Store diluted antibody with carrier protein (BSA 0.1 - 0.5%) at 4°C, stable for 2 weeks.

Biosafety Level: Not applicable (BSL-1)

References: 1. Lubberts, E., et al., Arthritis Rheum. 2004; 50(2): 650-659.
2. Cheng, X., et al., Atherosclerosis. 2011; 215(2): 471-474.

• Artikelnummer: BPS91015
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 91015
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Klonalität: Monoclonal
• Isotyp: IgG1κ