Anti-IL-3Ra (55A01)

Anti-IL-3Ra [55A01], Recombinant, IgG-Fc Fusion, Rabbit

CloneID: 55A01

Buffer Composition: PBS with 0.02% Proclin 300.

Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.

Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7

Uniprot Accession No.: P26951

Specificity Statement: This antibody is specific for the alpha subunit of IL-3R

Application Notes (Clone): The binding of the original version of this antibody (VHH) to IL3-Ra-expressing viral lipoparticles was characterized in an ELISA (K_D 17.1 nM). In a FACS binding assay, this antibody exhibited an EC₅₀ of 8.2 nM, 11 nM, and 1.1 nM for MOLM-13, THP-1, and HEK-IL-R3a, respectively, and an IC₅₀ of 40.0 nM in competition against clone 7G3. In its bi-specific constructions with clones 14D09 and 281F12, it served as an anchor (US20220242958).

• Artikelnummer: ABAAb04371-23.159
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab04371-23.159
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA, Fluorescence-Activated Cell Sorting (FACS)
• Isotyp: IgG-Fc Fusion
• Wirt: Rabbit