CloneID: 12-6-68
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice subcutaneously with 25 µg of human IL-4 in 100 µl of 150 mM sodium chloride emulsified with 100 µl of complete Freund’s adjuvant.
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P05112
Specificity Statement: This antibody binds human IL-4. Interleukin-4 is a cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses. It induces differentiation of naive helper T cells (Th0 cells) to Th2 cells. It also induces expression of class II MHC molecules on resting B-cells and enhances both secretion and cell surface expression of IgE and IgG1.
Application Notes (Clone): The binding of this antibody to human IL-4 was confirmed with ELISA (PMID: 12825686).
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