CloneID: OX-81
Heavy Chain modification: Fc Silent™
Antigen Long Description: OX-81 was prepared by immunizing BALB/c mice with full-length IL-4.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P20096
Specificity Statement: OX-81 binds specifically to IL-4. IL-4 is a globular signalling protein which is involved in the stimilation of activated B and T cell proliferation and the differentiation of B cells into plasma cells. IL-4 also regulates B cell class switching to IgE, upregulates MHC class II expression and plays a role in the inflammation response and wound repair.
Application Notes (Clone): OX-81 can be used to neutralise the effects produced by IL-4 and for FC studies.
Deutsch
English
