Anti-IL2R (AHT54)

Anti-IL2R [AHT54], Recombinant, IgG2a kappa, Mouse

CloneID: AHT54

Antigen Long Description: BALB/c mice were immunized with human T lymphoblasts and spleen cells of the immunized animals were fused with X63-Ag8.653 mouse myeloma cells. The supernatants of the resultant hybridomas were screened by a proliferation inhibition assay (inhibition of the human T lymphoblast response to IL-2). Two of those (the clones AHT54 and AHT107) that produced antibodies which inhibited IL-2 dependent proliferation of human T lymphoblasts were selected, cloned and recloned.

Buffer Composition: PBS only.

Uniprot Accession No.: P01589

Specificity Statement: AHT54 recognises a determinant close to the IL-2 binding site.

Application Notes (Clone): AHT54 has been used in ELISAs for the detection of soluble human IL-2R in response to different forms of helminthic and protozoal infections (O. Josimovic et al. 1988). AHT54 has also been shown to have anti-proliferative activities, and chimeric AHT54 antibodies with a human contant region have an increased inhibitory effect on proliferation of T lymphocytes (Rose 1992).

• Artikelnummer: ABAAb00902-2.0-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00902-2.0-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA, Flow Cytometry, Blocking
• Isotyp: IgG2a kappa
• Wirt: Mouse