Anti-Insulin-degrading Enzyme (Fab-IDE)

Anti-Insulin-degrading Enzyme [Fab-IDE], Recombinant, IgG1 kappa, Human

CloneID: Fab-IDE

Heavy Chain modification: Fc Silent™

Antigen Long Description: Human IDE.

Buffer Composition: PBS only.

Chimeric Use Statement: This full-length, chimeric human antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Uniprot Accession No.: P14735

Specificity Statement: Binds specificially to human IDE with a Kd of 3.72 nM.

Application Notes (Clone): This antibody binds human insulin degrading enzyme, which breaks down insulin as well as amyloid peptides and is suggested to play a role in both diabetes and Alzheimer's. Antibody binding does not affect steady-state kinetics of IDE.

• Artikelnummer: ABAAb00406-10.3-BT
• Hersteller: Absolute Antibody
• Hersteller Artikelnummer: Ab00406-10.3-BT
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: ELISA
• Isotyp: IgG1 kappa
• Wirt: Human