CloneID: Fab-IDE
Antigen Long Description: Human IDE.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P14735
Specificity Statement: Binds specificially to human IDE with a Kd of 3.72 nM.
Application Notes (Clone): This antibody binds human insulin degrading enzyme, which breaks down insulin as well as amyloid peptides and is suggested to play a role in both diabetes and Alzheimer's. Antibody binding does not affect steady-state kinetics of IDE.
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