CloneID: XMG1.2
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing a Lewis rat with soluble recombinant mouse IFN-γ.
Buffer Composition: PBS only.
Chimeric Use Statement: This is a reformatted mouse IgG2a Fc Silent™ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Uniprot Accession No.: P01580
Specificity Statement: This antibody is specific for mouse interferon gamma.
Application Notes (Clone): The original antibody (rat IgG1, κ) was effective in both ELISA and two blocking bioassays (Cherwinski et al., 1987; PMID: 2960769). This antibody was used successfully in flow cytometry (Sander et al., 1993; PMID: 8288874). This antibody was used in vivo to block and neutralize IFN-γ (Suzuki and Joh, 1994; PMID: 8202451) (Beatty and Paterson, 2001; PMID: 11160282).
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