Anti-Islet beta cells autoantigen (H116)

Anti-Islet beta cells autoantigen [H116], Recombinant, IgG1 kappa, Mouse
Artikelnummer
ABAAb03984-1.1-BT
Verpackungseinheit
1 mg
Hersteller
Absolute Antibody

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CloneID: H116

Antigen Long Description: The original antibody was generated from a B lymphocyte islet-infiltrate of a diabetes-resistant but insulitis-prone (8.3-NODxNOR) F1 mouse.

Origin Pub PMID: 18433871

Buffer Composition: PBS only.

Specificity Statement: This antibody is specific for an unknown autoantigen (still under investigation, as of 2016), expressed in islet beta cells (also referred to as intraislet).

Application Notes (Clone): This antibody recognizes antigenic determinants selectively expressed in islet β-cells of the pancreas, as determined by immunofluorescence (IF) staining; its staining pattern mimics the pattern obtained with anti-insulin antibodies. Furthermore, this antibody was shown to be cross-reactive with stomach and kidney cryosections of NOD.RAG-2−/− mice (Carrillo et al., 2005; PMID: 15616012). This antibody was also used for tissue immunostaining of pancreatic cryosections from NOD.RAG-2−/− mice (Carrascal et al., 2016; PMID: 26639224).
Mehr Informationen
Artikelnummer ABAAb03984-1.1-BT
Hersteller Absolute Antibody
Hersteller Artikelnummer Ab03984-1.1-BT
Verpackungseinheit 1 mg
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Rat (Rattus)
Klonalität Recombinant
Methode Immunofluorescence
Isotyp IgG1 kappa
Wirt Mouse
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