CloneID: 27.4.1
Antigen Long Description: The original antibody was generated by immunizing BALB/c mice with streptococcal M type 5 membranes followed by a second, boosting dose of Lysin M5.
Origin Pub PMID: 11282394
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P02977
Specificity Statement: This antibody reacts with α-helical molecules. Specifically, it binds streptococcal M-protein (type 5), human myosin, keratin, tropomyosin, ganglioside, and glycophorin M,N.
Application Notes (Clone): This antibody reacts with the human retina, as shown in an indirect immunofluorescence assay. This antibody reacts with retinal S-antigen (S-Ag), as shown in an ELISA (Lerner et al., 1995; PMID: 8722579). This antibody binds myosin at a high relative avidity, as determined in a competitive ELISA. Reactivity with glycophorin M and N was determined by hemagglutination assay (Mertens et al., 2000; PMID: 11282394).
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