CloneID: 1032
Heavy Chain modification: Fc Silent™
Antigen Long Description: The original antibody was generated by immunizing a BALB/c mouse with major vault protein.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: Q14764
Specificity Statement: This antibody is specific for the human major vault protein.
Application Notes (Clone): The original version of this antibody was used for an immunohistochemistry experiment on human FFPE tissue blocks (Ramberg et al., 2021; PMID:33609362), on MCF-7 breast cancer cells (Abbondanza et al., 1998; PMID:9628887). Further this antibody was used for immunohistochemistry on cervix carcinoma tissues (Lloret et al., 2009; PMID:19251084), on human lung tissue (Schroeijers et al., 2001; PMID:11668191). Finally, a western blot on human liver tumour and nontumor tissue lysates was performed using this antibody (Megger et al., 2013; PMID:23462207).
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