CloneID: K42-IL
Heavy Chain modification: Fc Silent™
Antigen Long Description: Bovine rod cell disc membranes.
Origin Pub PMID: 16407202
Buffer Composition: PBS with 0.02% Proclin 300.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Uniprot Accession No.: P02699
Specificity Statement: The antibody binds specifically to the C3-loop of metarhodpsin-I with a Kd of 2.8 nM, the epitope being TGALQERSK.
Application Notes (Clone): This antibody specifically binds to the C3-loop of metarhodopsin-I, which is in equilibrium with the meta-active metarhodopsin II. The antibody stabilises the inactive metarhodopsin-I, inhibiting G-protein activation.