CloneID: OX-27
Heavy Chain modification: Fc Silent™
Antigen Long Description: This antibody was prepared by immunizing BALB/c mice with rat phytohemagglutinin blasts.
Buffer Composition: PBS with 0.02% Proclin 300.
Chimeric Use Statement: This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Available Custom Conjugation Options: AP, HRP, Fluorescein, APC, PE, Biotin Type A, Biotin Type B, Streptavidin, FluoroProbes 647H, Atto488, APC/Cy7, PE/Cy7
Specificity Statement: This antibody recognizes a polymorphic determinant (c haplotype) of rat Class I MHC Antigen (RT-1A).
Application Notes (Clone): This antibody binds to rat MHC Class I, and has been used to show that, in an in vivo rat model, antibodies against MHC class I antigens from stored blood may precipitate transfusion-related acute lung injury (Kelher, 2009).
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